Microbiology

Bacteria growing on agar in a petri dish

Our concerns in the Microbiology research area cover various aspects, including antibiotic resistance, the inter-relationship between microorganisms and disease (including cancer and inflammation), and the surveillance of novel pathogens.

Dr Helen McRobie focuses her research interests around the pharmacological characterisation and pleiotropy of the MC1R gene. Her work on the genetic basis of melanism in grey, fox, red and palm squirrels was the basis of the Black Squirrel Project.

Dr Caray Walker researches the mechanisms used by these bacteria to establish infection. Particular emphasis is on how environmental factors, such as iron, regulate gene expression and the importance of these mechanisms in the infection process.

Dr Chris O’Kane conducts research into the development of novel therapeutics for antimicrobial resistance, and the application of nanotechnology in the development of theranostic devices.

Dr Clett Erridge has a primary research interest in mechanisms connecting inflammation to lipid metabolism, particularly in the context of coronary artery disease and other inflammatory conditions associated with the liver. His interest also encompass the impact that the gut microbiota can have on the immune system and in drug discovery technologies.

Dr Don Keiller has a current research interest in the genomics and proteomics of chlamydia, which is a collaborative project with Addenbrooke's Hospital and the Sanger Institute.

The Microbiology research area is part of the Biomedical Research Group.

We offer our Biomedical Science PhD. We've also identified a range of innovative research project opportunities for you as a postgraduate researcher.

Members

Find out more about our members by exploring their staff profiles.

News

Grant won to support doctoral researcher


Key publications

Mitchell, J.A., Cardwell, J.M., Leach, H., Walker, C.A., Le Poder, S., Decaro, N., Rusvai, M., Egberink, H., Rottier, P., Fernandez, M., Fragkiadaki, E., Shields, S. and Brownlie, J., 2017. European surveillance of emerging pathogens associated with canine infectious respiratory disease. Vet Microbiology, (212), pp.31-38.

Sheng, Y., Beguin, E., Nesbitt, H., Kamila, S., Owen, J., Barnsley, LC., Callan, B., O'Kane, C., Nomikou, N., Hamoudi, R., Taylor, MA., Love, M., Kelly, P., O'Rourke, D., Stride, E., McHale, AP. and Callan, JF., 2017. Magnetically responsive microbubbles as delivery vehicles for targeted sonodynamic and antimetabolite therapy of pancreatic cancer. Journal of Controlled Release (262), pp.192-200.

Herbert, KE. and Erridge, C., 2018. Regulation of low-density lipoprotein cholesterol by intestinal inflammation and the acute phase response. Cardiovascular Research, 2(114), pp.226-232.