Our Biomedical Research Group (BRG) aims to integrate research into the genotypic and phenotypic relationships underpinning our understanding of health and disease.
We're a diverse research group with interests in biochemical and molecular mechanisms that underpin the pathogenesis and aetiology of mammalian diseases, such as rheumatoid arthritis, myeloproliferative diseases, inflammation, thrombosis, tumorigenesis, vascular injury, and diabetes. Additionally, we have interests in G-protein coupled receptor signalling, the genetics of antibiotic resistance, virulence and evolution of bacteria.
The Biomedical Research Group is located in the new Science Centre, a £45M state of the art teaching and research facility. Included in the centre are dedicated research laboratories with space for more than fifty staff and postgraduate students, providing specialist tissue culture, molecular biology and microbiology research spaces. The centre incorporates a 300-seat lecture theatre adapted for science teaching and a 200-station biosciences laboratory.
If you're part of an organisation, biomedical science provider, or research group who wishes to collaborate or explore possible areas of research our specialisms might support, then please contact Dr Nicholas Pugh, our Deputy Head of Department for Research, or a member of the Biomedical Research Group.
Headed by Dr Peter Coussons, the Biomedical Research Group is grouped into several specialist research areas which include:
Find out more about our members by exploring their staff profiles.
Dr Joseph Bird - Skeletal disorders, ageing mechanisms and vascular disease
Dr Havovi Chichger - Vascular disease and diabetes
Dr Peter Coussons - Transglutaminase enzymes, cancer, antioxidants, catalytic antibodies, erythropoietin and rheumatoid arthritis
Dr Paul Dyer - Drug delivery
Dr Clett Erridge - Innate immunity, atherosclerosis, and microbiota
Dr Richard Jones - Macular degeneration
Dr Don Keiller - Exercise stress physiology, genomics, and proteomics of chlamydia
Dr Linda King - Lipotoxicity and impairment of insulin signalling in type II diabetes
Dr Helen McRobie - Melanism in the grey squirrel, mechanisms of antibiotic resistance
Dr Chris O’Kane - DNA nanotechnology, cancer biology and pharmaceutical nanoscience
Prof Christopher Parris - Human cancer and DNA repair
Dr Claire Pike - Cancer, molecular biology, molecular genetics, epigenetics
Dr Grisha Pirianov - Regulation of the inflammatory response, proinflammatory mediators, tol-like receptors, anti-inflammatory drugs
Dr Nicholas Pugh - Platelet signalling pathways
Dr Felicity Savage - Colonic wound healing, inflammatory bowel disease
Dr Jim Sullivan - Ubiquitin, post-translational modification, protein trafficking
Dr Caray Walker - Pathogenesis of bacterial animal pathogens
Hollie Allison and Katie Choi, biomedical science students at our University, have both received a £2000 summer studentship from the Wellcome Trust. Hollie is isolating and identifying antibiotic-resistant strains of bacteria from dog faeces found in recreational areas of Cambridge. Katie Choi is working on the development of novel therapeutics against antibiotic resistance.