Dr Lorna A. Nisbet

Lecturer

Faculty:Faculty of Science and Engineering

Department:School of Life Sciences

Location: Cambridge

Areas of Expertise: Analytical Chemistry , Forensic science and crime

Lorna's research interests lie within the field of forensic toxicology, specialising in the detection of new psychoactive substances in biological matrices.

lorna.nisbet@anglia.ac.uk

Background

Lorna obtained her BSc (Hons) in Analytical Chemistry from the University of Strathclyde, Glasgow, before completing her MSc in Forensic Toxicology at the University of Glasgow. Lorna then went on to obtain her PhD in Forensic Toxicology at the University of Glasgow under the supervision of Dr Karen S. Scott and Dr Fiona M. Wylie focusing on the detection of new psychoactive substances in biological matrices. As part of her PhD Lorna spent 15 months carrying out research at the Fredric Rieders Family Foundation in Philadelphia, USA. Whilst in Philadelphia Lorna also taught at Arcadia University. Lorna joined ARU in April 2016

Research interests

  • Forensic toxicology
  • New psychoactive substances
  • Alternative matrice
  • Work place drug testing
  • Drug prevalence

Teaching

BSc (Hons) in Forensic Science with Foundation Year
Module Leader for Chemical Principles
Contributes to Case Studies in Forensic and Investigative Sciences

BSc (Hons) in Forensic Science
Module Leader for Project Preparation
Module Leader for Forensic Analysis of Drugs and Poisons

BSc (Hons) in Crime and Investigative Studies
Module Leader for Project Preparation
Contributes to United Kingdom Legal Systems and Law for Forensic Scientists

Qualifications

PhD, Forensic Toxicology – University of Glasgow
MSc, Forensic Toxicology – University of Glasgow
BSc (hons.), Forensic and Analytical Chemistry- Strathclyde University
PGCert in Higher Education and Learning - Anglia Ruskin University

Memberships, editorial boards

Society of Forensic Toxicology
American Academy of Forensic Science
United Kingdom and Ireland Association of Forensic Toxicologists
Royal Society of Chemistry
Council for Forensic Science Educators
London Toxicology Group

Research grants, consultancy, knowledge exchange

Consultancy
North Wales Police

Grants
RSC Research Fund Grant (RF18-2379) - "Identification of mexedrone metabolites using human liver microsomes and gas chromatography-mass spectrometry". £4000, Dec 2017

RSC Analytical Division Travel Grant to attend the SOFT/TIAFT meeting, Boca Raton, FL, £700, July 2017

Awards
Experiment Design and Impact in Toxicology (EDIT) award presented by the Journal of Analytical Toxicology (Jan 2018) -Nisbet, L.A., Venson, R., Wylie, F.M. and Scott, K.S., 2017. Application of a Urine and Hair Validated LC–MS-MS Method to Determine the Effect of Hair Color on the Incorporation of 25B-NBOMe, 25C-NBOMe and 25I-NBOMe into Hair in the Rat. Journal of analytical toxicology, 41(6), pp.559-565.

SOFT ERA award (October 2016) - $2000 - Optimisation of a GC-MS method for the quantitative identification of 23 New Psychoactive Substances in blood and urine

FSF Student Scholarship Award (2014) - Comparison of Solid Phase Extraction (SPE) and Supported Liquid Extraction (SLE) Columns for the Extraction of 23 Novel Psychoactive Substances from Blood and Urine

UCT’S Excellence in SPE award (October 2014) - Short-Term Stability of Mephedrone in Blood and the Impact of Storage Conditions on Concentrations Detected by GC/MS

United Kingdom & Ireland Association of Forensic Toxicologist Student Analytical Methods Poster Prize (September 2014) Optimization of Derivatisation for New Psychoactive Substances (Cathinone’s and NBOMe’s)

Academy of Forensic Science Annual Meeting Toxicology Section Best Poster Award (February 2014) - $1000 Short-Term Stability of Mephedrone in Blood and the Impact of Storage Conditions on Concentrations Detected by GC/MS

United Kingdom & Ireland Association of Forensic Toxicologist Student Analytical Methods Poster Prize (September 2010) In-Vitro Conversion Between GHB, GBL & 1,4-BD

Selected recent publications

Nisbet, L.A., Venson, R., Wylie, F.M. and Scott, K.S., 2017. Application of a Urine and Hair Validated LC–MS-MS Method to Determine the Effect of Hair Color on the Incorporation of 25B-NBOMe, 25C-NBOMe and 25I-NBOMe into Hair in the Rat. Journal of analytical toxicology, 41(6), pp.559-565.

Recent presentations and conferences

Invited Speaker for the LTG/UKIAFT UKIAFT joint meeting. “Application of a Urine and Hair Validated LC–MSMS Method to Determine the Effect of Hair Color on the Incorporation of 25B-NBOMe, 25C-NBOMe and 25I-NBOMe into Hair in the Rat”, March 2018

"Development of a Gas Chromatography-Mass Spectrometry Method for Mexedrone in Urine". Lorna A. Nisbet, PhD, Maiken Larsen, Karen S. Scott, PhD. Society of Forensic Toxicologists (SOFT)/The International Association of Forensic Toxicologists (TIAFT) 2017 Joint Meeting. Boca Raton, FL. September 2017.

"Stability of Mephedrone, Naphyrone, and MDPV in Solvents and Na2EDTA-Preserved Human Whole Blood," Heather L Ciallella, Lorna A Nisbet, Simeon O Kotchoni, Alex J Krotulski, MSFS, and Karen S Scott. Society of Forensic Toxicologists (SOFT)/The International Association of Forensic Toxicologists (TIAFT) 2017 Joint Meeting. Boca Raton, FL. September 2017. 

Invited speaker for the Chartered Society of Forensic Science “GC/MS and LC/MS methodology for NPS detection and measurement” Warrington, UK, June, 2017.

"An Assessment of the Stability of Mephedrone in Solvents and Biological Matrices," Heather L. Ciallella, Lorna A. Nisbet, Simeon O. Kotchoni, Alex J. Krotulski, and Karen S. Scott. American Academy of Forensic Sciences (AAFS) 69th Annual Scientific Meeting. New Orleans, LA. February 2017.

"Stability of Synthetic Cathinones in Biological and Non-Biological Matrices," Heather L. Ciallella, Lorna A. Nisbet, and Karen S. Scott. Eastern Analytical Symposium (EAS) & Exhibition. Somerset, NJ. November 2016.

Optimisation of a GC-MS method for the quantitative identification of 23 New Psychoactive Substances in blood and urine, Lorna A Nisbet and Karen S Scott, Paper presented at the Society of Forensic Toxicologists annual meeting, Dallas, US, October 2016

Analysis and detection of 25B, 25C and 25I-NBOMe in rat hair using SPE/LC/MSMS,Lorna A Nisbet, Rafael Venson, Fiona M Wylie and Karen S Scott,  SOFT- Atlanta, October 2015.

Invited speaker for the Society of Forensic Toxicology workshop Sample preparation "Sample preparation using SPE & SLE: Advantages, disadvantages and practical applications" SOFT- Atlanta, October 2015.

Comparison of SPE Cartridges for the Extraction of 25 New Psychoactive Substances, Lorna A Nisbet, and Karen S Scott, Scottish Student Forensic Research Symposium, Dundee, March 2015.

Comparison of SPE and SLE columns for the extraction of 23 novel psychoactive substances from blood and urine, Lorna A Nisbet, and Karen S Scott, AAFS- Orlando, February 2015.

In-Vitro Conversion Between GHB, GBL & 1,4-BD, Lorna A Nisbet, and Karen S Scott, Paper presented at the Society of Forensic Toxicologists annual meeting, Grand Rapids, MI, USA, 2014.

Comparison of SPE cartridges for the extraction of 25 new psychoactive substances, Lorna A Nisbet, and Karen S Scott, Paper presented at the Society of Forensic Toxicologists annual meeting, Grand Rapids, MI, USA, 2014.

Development and Validation of a Method for Analysis NBOMe Drugs in Blood, Plasma and Urine by LC-MS/MS, McGrath M, Nisbet L, Logan BK, Scott KS, Paper presented at the Society of Forensic Toxicologists annual meeting, Grand Rapids, MI, USA, 2014.

Optimization of derivatization for new psychoactive substances (cathinones & NBOMe’s), Lorna A Nisbet, Jakub Klobut and Karen S Scott,  United Kingdom and Ireland Association of Forensic Toxicology (UKIAFT)-Leicester, September 2014.

Invited Speaker United Kingdom and Ireland Association of Forensic Toxicology "Comarison of SPE cartridges for the extraction of 25 new psychoactive substances”, United Kingdom and Ireland Association of Forensic Toxicology (UKIAFT)-Leicester, September 2014.

Short-Term Stability of Mephedrone in Blood and the Impact of Storage Conditions on Concentrations Detected by GC/MS,  Lorna A Nisbet, and Karen S Scott, American Academy of Forensic Sciences, February 2014

Media experience

Naked Scientist "Criminal Chemistry - What's Your Poison" (January 2018)