Dr Sarah Jane Lockey

Senior Lecturer in Pharmacology

Faculty:Faculty of Health, Education, Medicine and Social Care

Department:School of Medicine

Location: Chelmsford

Sarah Jane is a senior lecturer in pharmacology and has a special interest in active learning styles in undergraduate medical curriculums, particularly in the themes of physiology and pharmacology.

Background

Sarah Jane graduated in BSc Applied Physiology and Pharmacology from the University of the West of England, Bristol, in 2005.

In 2009, she received an MPhil in molecular epidemiology at Southampton University, where she was a medical demonstrator, before joining the Physiology teaching team at Keele University Medical School as an Associate Teaching Fellow where she gained her PGCert Higher Education and PGDip Medical Education.

She went on to complete a PhD in Sport and Genetics at Manchester Metropolitan University. Here, with the support of Sports Genomics Laboratory, MMU she worked alongside London Marathon to recruit the largest cohort of Caucasian national and international marathon runners for her research into the genetics of human performance.

In 2015. Sarah Jane joined Newcastle University School of Medicine as a Teaching Fellow in Pharmacology and went on to co-lead the Clinical Pharmacology Therapeutics and Prescribing strand. Following that, she joined the School of Medicine at Anglia Ruskin University in Chelmsford, as our academic lead for pharmacology.

Sarah Jane has a keen interest in undergraduate medical education, particularly active learning styles in the areas of physiology and pharmacology. She was appointed a fellow of the Higher Education Academy in 2016, a Fellow of the Staff and Educational Development Association in 2012 and has been a member of ASME since 2011.

Research interests

  • Student and staff use of intended learning outcomes.
  • Active learning styles in undergraduate medical education.
  • Laboratory based teaching in undergraduate medical education.
  • Game theory in medical education.
  • The genetics of elite marathon performance.

Elite endurance athletes tend to have differing genetic profiles from less successful athletes and non-athletes. Developing knowledge in this area, providing a more detailed analysis of the genetic constitution of elite marathon athletes than that done previously and identifying an ‘advantageous’ genetic profile in elite marathon athletes would be a significant development. The insight provided about the underlying physiological mechanisms has implications for both sport and also exercise for the prevention and treatment of disease.

Areas of research supervision

Previously co-supervised four post-graduate research students.

Teaching

Sarah Jane's primary teaching and learning roles are the co-ordination and delivery of the undergraduate pharmacology content to MBChB students at Anglia Ruskin University School of Medicine. Now focusing on Medical education, Sarah Jane continues to ensure learning is underpinned with theoretical insights from the literature. She has experience of delivery on traditional, integrated and PBL based medical curriculums. Sarah Jane is also a personal tutor providing academic and pastoral support to MBChB students in pre-clinical years.

Qualifications

  • PHD, The Genetic Profiles of Elite Athlete's, Manchester Metropolitan University.
  • MPhil Molecular Epidemiology, University of Southampton.
  • PG Dip Medical Education, Keele University.
  • PG Cert Teaching and Learning in Higher Education Keele University.
  • BSc (Hons) Applied Physiology and Pharmacology, University of the West of England.

Memberships, editorial boards

  • HEA Fellow
  • The Physiological Society
  • ASME
  • Staff and Educational Development Association Fellow
 

Selected recent publications

ID. Papadimitriou, SJ. Lockey, S. Voisin, AJ. Herbert, F. Garton, Houweling, PJ, Cieszczyk, P, Maciejewska-Skrendo, A, Sawczuk, M, Massidda, M, Calò, CM, Druzhevskaya, AM, Astratenkova, IV, Kouvatsi, A, Ahmetov, II, Jacques, M, Stebbings, G, Heffernan, SM, Day, SH, Erskine, RM, Pedlar, C, Kipps, C, North, KN, Williams, AG, Eynon, N (2018). No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes. BMC Genomics. 19(1), https://doi.org/10.1186/s12864-017-4412-0.

Stebbings GK, Williams AG, Herbert AJ, Lockey SJ, Heffernan SM, Erskine RM, Morse CI, Day SH. (2018). TTN genotype is associated with fascicle length and marathon running performance. Scand J Med Sci Sports.28:400–406. http://doi.org/10.1111/sms.12927.

Stebbings GK, Williams AG, Herbert AJ, Lockey SJ, Heffernan SM, Erskine RM, Morse CI, Day SH. Titin genotype is associated with skeletal muscle fascicle length in recreationally active men and running performance in habitually trained marathon runners. British Journal of Sports Medicine 50:1. http://dx.doi.org/10.1136/bjsports-2016-097120.96.

Heffernan SM, Kilduff LP, Erskine RM, Day SH, McPhee JS, McMahon GE, Stebbings GK, Neale JP, Lockey SJ, Ribbans WJ, Cook CJ, Vance B, Raleigh SM, Roberts C, Bennett MA, Wang G, Collins M, Pitsiladis YP, Williams AG. Mar 2016. Association of ACTN3 R577X but not ACE I/D gene variants with elite rugby union player status and playing position. Physiol Genomics. 48(3):196-201. https://doi.org/10.1152/physiolgenomics.00107.2015.

Seth-Smith HM, Harris SR, Persson K, Marsh P, Barron A, Bignell A, Bjartling C, Clarke L, Cutcliffe LT, Lambden PR, Lennard N, Lockey SJ, Quail MA, Salim O, Skilton RJ, Wang Y, Holland MJ, Parkhill J, Thomson NR, Clarke IN. 2009. Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain. BMC Genomics 10: 239.

Thomson NR, Holden MT, Carder M, Lennard N, Lockey SJ, Marsh P, Skipp P, O'Connor CD, Goodhead I, Norbertzcak H, Harris B, Ormond D, Rance R, Quail MA, Parkhill J, Stephens RS, Clarke IN. 2007. Chlamydia trachomatis: Genome sequence analysis of lymphogranuloma venereum isolates. Genome Research 18, 161-171.

Recent presentations and conferences

Herbert AJ, Williams AG, Lockey SJ, Erskine RM, Hennis PJ, Sale C, Day SH, Stebbings GK. 2017 Associations of bone mineral density-related genes and marathon performance in elite European caucasian marathon runners December 2017. British Journal of Sports Medicine 51(Suppl 2):A2.1-A2. doi:10.1136/bjsports-2017-098966.4. Conference: International Sports Science + Sports Medicine Conference 2017 ABSTRACTS, Incorporating Sports Physiotherapy and Strength & Conditioning, Newcastle Upon Tyne, England 5–7 September 2017.

Stebbings G, Herbert AJ, Brazier J, Lockey SJ, Erskine RM, Day SH, Williams AG, 2017. No association between tendon-related genes and performance in elite European Caucasian marathon runners. December 2017. British Journal of Sports Medicine 51(Suppl 2):. doi:10.1136/bjsports-2017-098966.4. Conference: International Sports Science + Sports Medicine Conference 2017 ABSTRACTS, Incorporating Sports Physiotherapy and Strength & Conditioning, Newcastle Upon Tyne, England 5–7 September 2017.

Stebbings GK, Williams AG, Herbert AJ, Lockey SJ, Heffernan SM, Erskine RM, Morse CI, Day SH. 2016. Titin genotype is associated with skeletal muscle fascicle length in recreationally active men and running performance in habitually trained marathon runners. British Journal of Sports Medicine 50:1. http://dx.doi.org/10.1136/bjsports-2016-097120.96.

Lockey SJ, Erskine RM, Pedlar C, Kipps CWG, Heffernan SM, Herbert AJ, Stebbings GK, Williams AG, Day, SH. 2015. The individual and combined association between multiple gene polymorphisms and elite endurance athlete status. Book of Abstracts of the 20th Annual Congress of the European College of Sport Science in Malmö, Sweden  European Database of Sport Science.

Adam J Herbert, Alun G Williams, Sarah J Lockey, Robert M Erskine, Shane M Heffernan, Charles R Pedlar, Courtney Kipps, Stephen H Day, Georgina K Stebbings. ACTN3 R577x genotype is not associated with elite European caucasian marathon performance. British Journal of Sports Medicine 50:1. http://dx.doi.org/10.1136/bjsports-2016-097120.94.

Lockey SJ, Erskine RM, Herbert AJ, Pedlar CR, Kipps CG, Williams AG, Day SH. 2014. ACTN3 R577X genotype is not associated with elite marathon runners. Physiology 2014 (London, UK) Proc Physiol Soc 31, PCA158.