Faculty:Faculty of Medical Science
Department:School of Medicine
Professor White is a Consultant Clinical Scientist and is the Head of Clinical Engineering at Cambridge University Hospitals NHS Foundation Trust. He is responsible for medical technology, equipment strategy, research and innovation. He has an international reputation in cardiovascular research in the area of ventricular dynamics and energetic.
In 1994 he was awarded an MSc in Biomedical Engineering from the University of Surrey and a PhD and DIC through Imperial College London in 1998. His research interests have specialised in physiological measurement of the cardiovascular system. It is in the area of ventricular dynamics and energetics, that he has made a significant contribution, both nationally and internationally. He was awarded the Spiers Prize, of the Institute of Physics and Engineering in Medicine (IPEM) in 1997, and the Founders prize in 2002 for his outstanding contribution to Medical Physics and Clinical Engineering, and was awarded an IPEM and Royal College of Physicians Essay Prize in 2006 for his work developing a novel technique to measure heart function immediately after a non surgical closure of an atrial septal defect. In 2010 he was awarded an East of England Senior Clinical Academic Fellowship. In 2017 he was awarded the Department of Health Chief Scientific Officers Health Care Scientist of the Year Award for leadership, innovation and research, and runner up in the Lord Carter innovation awards.
He has written numerous peer reviewed papers, reviews and book chapters. He lectures nationally and internationally and has worked in Europe, Canada and Australia. He has also supervised and guided many students with MSc, PhD, and MD projects or attachments as part of their recognised training programmes. He has actively developed collaborative academic and industrial links with companies both in the United Kingdom and abroad. He actively reviews papers on Clinical Engineering and Physiological Measurement for a number of peer reviewed journals. In 2007 he sat on the editorial board for the journal “Physiological Measurement”. He was part of the curriculum development group for the Scientist Training Programme under Modernising Scientific Careers, and has also sat on the Higher Specialist Scientific Training Curriculum development board for Clinical Biomedical Engineering on behalf of the Royal College of Surgeons and Royal College of Practioners. He has held a number of positions in the Institute of Physics and Engineering in Medicine (IPEM). He was secretary for the physiological measurement special interest group, chaired its accreditation and training panel, became the first director of the Professional Standards Board and was Vice President for Professional Issues chairing its Professional Advisory Group. He was a trustee, and Vice president for Industry and chaired its Industrial Advisory group. He is currently on the affiliated faculty of Cambridge Digital Innovation (CDI) and sits on Cambridge University Health Partners Expert Innovation Panel, Addenbrookes Charitable Trust Professional Advisory panel, and Addenbrookes Charitable Trust Innovation Panel. He has recently been invited to sit on the Chief scientific Officers Leadership, Improvement and Advice (LIA) Group.
Effective Arterial Elastance Detects Occult RV Dysfunction in Chronic Thromboembolic Pulmonary Vascular Disease. Axell RG, Messer SJ, White PA, McCabe C, Statopoulou T, Drozdzynska M, Viscasillas, J, Hinchy EC, Hampton-Till J, Alibhai HI, Morrell N, Pepke-Zaba J, Large SR, Hoole SP. Physiol. Rep. 5 (7), 2017, e13227,doi: 10.14814/phy2.13227
Stunning and Right Ventricular Dysfunction Is Induced by Coronary Balloon Occlusion and Rapid Pacing in Humans: Insights From Right Ventricular Conductance Catheter Studies. Axell RG, Giblett JP, White PA, Klein A, Hampton-Til J, O'Sullivan M, Braganza D, Davies WR, West NEJ, Densem CG, Hoole SP. J Am Heart Assoc. 2017;6:e005820. DOI: 10.1161/JAHA.117.005820.
Rapid Pacing Induced Right Ventricular Dysfunction is Evident after Balloon Expandable Trans-femoral Aortic Valve Replacement. Axell RG, White PA, Giblett JP, Williams L, Rana BS, Klein A, Hampton-Till J, O’Sullivan M, Davies WR, Densem CG, Hoole SP. J Am Coll Cardiol. 2017 Feb 21;69(7):903-904
Functional assessment and transplantation of the donor heart after circulatory death. Messer SJ, Axell RG, Colah S, White PA, Ryan M, Page AA, Parizkova B, Valchanov K, White CW, Freed DH, Ashley E, Dunning J, Goddard M, Parameshwar J, Watson CJ, Krieg T, Ali A, Tsui S, Large SR. J Heart Lung Transplant. 2016 Dec;35(12):1443-1452
The diastolic backwards-travelling decompression (suction) wave correlates with simultaneously acquired indices of diastolic function and is reduced in left ventricular stunning. Ladwiniec A, White PA, Nijjer SS, O’Sullivan M, West NEJ, Davies JE, Hoole SP.Circ Cardiovasc Interv. 2016 Sep;9(9).
Glucagon-like peptide-1 derived cardioprotection does not utilize a KATP-channel dependent pathway: mechanistic insights from human supply and demand ischemia studies Giblett JP, Axell RG, White PA, Clarke SJ, McCormick L, Read PA, Reinhold J, Brown AJ, O’Sullivan M, West NEJ, Dutka DP, Hoole SP Cardiovasc Diabet. 2016 15:99
Ventricular SW – Ea relationship can detect RV dysfunction in CTED. Axell RG, Messer S, White PA, McCabe C, Cannon J, Large SR, Pepke – Zaba J, Hoole SJ. Journal of the American College of Cardiology 2016 (Apr) 67(13):2058
Conductance catheter derived right ventricular diastolic dysfunction is evident after rapid pacing test capture prior to transcatheter aortic valve replacement. Axell RG, White PA, Rana BS, Klein A, O’Sullivan M, Shapiro L, Densem CG, Hoole S. Journal of the American College of Cardiology 2016 (Apr) 67(13):119 ·
Pre-treatment with glucagon-like peptide-1 protects against ischemic left ventricular dysfunction and stunning without a detected difference in myocardial substrate utilization. McCormick LM, Hoole SP, White PA, Read PA, Axell RG, Clarke SJ, O’Sullivan M, West NEJ, Dutka DP. JACC: Cardiovascular Interventions 2015; 8(2): 292-301.
RV diastolic dysfunction: time to re-evaluate its importance in heart failure. Axell, RG, Hoole SP, Hampton-Till J, White PA. Heart failure reviews 2015: 1-11.
Clinical Engineering: A Handbook for Clinical and Biomedical Engineers. (Eds) Taktak AFG, Ganney P, Long D, White PA 2013 Academic Press.
Pressure and Flow. White PA, Axell RG. In: Clinical Engineering: A Handbook for Clinical and Biomedical Engineers. (Eds) Taktak AFG, Ganney P, Long D, White PA 2013 Academic Press.
Respiratory. Tunicliffe E, White PA. In: Clinical Engineering: A Handbook for Clinical and Biomedical Engineers. (Eds) Taktak AFG, Ganney P, Long D, White PA 2013 Academic Press.
Haemodynamic Monitoring - General Principles. White PA, Klein A. In: Core Topics in Cardiothoracic Critical Care. (Eds) Klein A, Vuylsteke A, Nashef S. 2007 Cambridge University Press.
Ventricular Performance. White PA, Arrowsmith JE. In: Core Topics in Cardiac Anaesthesia. (Eds) Mackay JH, Arrowsmith JE. 2004 Greenwich Medical Media Limited.
Professor White has been an invited speaker at many conferences both in the UK, Europe ,and USA and has given talks around all aspects of Clinical Engineering and Clinical Measurement.