Dr Jufen Zhang

Medical Statistician, Clinical Trials Unit, Postgraduate Medical Institute

Faculty:Faculty of Medical Science

Location: Chelmsford

Dr Zhang is a Medical Statistician. She is interested in clinical trials research and application of statistical methods to analyse clinical data.

Email: Jufen.Zhang@anglia.ac.uk


Dr Jufen Zhang received her PhD from the University of Exeter. Before joining Anglia Ruskin University, she worked as a Statistical Analyst at the University of Hull.


  • PhD in Statistical Computing
  • MSc in Applied Statistics and Operational Research
  • BSc in Mathematics
  • Chartered Statistician, Royal Statistical Society

Selected recent publications

Pellicori P, Cleland JG, Zhang J, Bennett A, Urbinati A, Shah P, Kazmi S, Clark AL. Cardiac Dysfunction, Congestion and Loop Diuretics: Their Relationship to Prognosis in Heart Failure. Cardiovascular Drugs and Therapy, in press

Jufen Zhang, Riet Dierckx, Kevin Mohee, Andrew L. Clark, John G. Cleland. Xanthine Oxidase Inhibition for the Treatment of Cardiovascular Disease: An Updated Systematic Review and Meta-Analysis. ESC Heart Failure (2016)

Cleland JG, Zhang J, Pellicori P, Dicken B, Dierckx R, Shoaib A, Wong K, Rigby A, Goode K, Clark AL. Prevalence and Outcomes of Anemia and Hematinic Deficiencies in Patients with Chronic Heart Failure. JAMA Cardiol. 2016 Aug 1;1(5):539-47

Jufen Zhang, James Hobkirk, Sean Carroll, Pierpaolo Pellicori, Andrew L. Clark, John G.F. Cleland. Exploring quality of life in patients with and without heart failure. International Journal of Cardiology 202 (2016) 676–684

Pierpaolo Pellicori, Anil C. Joseph, Jufen Zhang, Elena Lukaschuk, Nasser Sherwi, Christos V. Bourantas, Huan Loh, Andrew L. Clark, John GF Cleland. The Relationship of QRS Morphology with Cardiac Structure and Function in Patients with Heart Failure. Clin Res Cardiol. 2015 Nov;104(11):935-45

Pierpaolo Pellicori, Jufen Zhang, Elena Lukaschuk, Anil C Joseph, Christos V Bourantas, Huan Loh, Thanjavur Bragadeesh, Andrew L Clark, John GF Cleland. Left Atrial Function Measured by Cardiac Magnetic Resonance Imaging in Patients with Heart Failure: Clinical Associations and Prognostic Value. European Heart Journal (2015) 36, 733–743

Farag Mohamed, Mabote Thato, Shoaib Ahmad, Zhang Jufen, Nabhan Ashraf F, Clark Andrew L, Cleland John G. Hydralazine and Nitrates Alone or Combined for the Management of Chronic Heart Failure: A Systematic Review. International Journal of Cardiology (2015), pp. 61-69

Dierckx R, Cleland JGF, Pellicori P, Zhang J, Clark AL. "If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment?" Journal of Telemedicine and Telecare, 2015, 0(0) 10-9

Pierluigi Costanzo, MD, MSc; John G.F. Cleland, MD; Pierpaolo Pellicori, MD; Andrew L. Clark, MD; David Hepburn, MD; Eric S. Kilpatrick, MD; Pasquale Perrone-Filardi, MD, PhD; Jufen Zhang, MSc, PhD; and Stephen L. Atkin, MD, PhD. The Obesity Paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis: A Cohort Study. Ann Intern Med. 2015;162(9):610-618

Pierpaolo Pellicori, Anna Kallvikbacka-Bennett, Riet Dierckx, Jufen Zhang, Paola Putzu, Joe Cuthbert, Vennela Boyalla, Ahmed Shoaib, Andrew L Clark, John GF Cleland. Prognostic Significance of Ultrasound-Assessed Jugular Vein Distensibility in Heart Failure, Heart 2015 Jul;101(14):1149-58

Nasser Sherwi, Kenneth Wong, Jufen Zhang, Pierpaolo Pellicori, Olga Khaleva, Christos Bourantas, Azam Torabi, Andrew Clark and John G Cleland. The Prevalence of Extra-cranial Carotid Artery Disease in Chronic Heart Failure. Cardiology and Angiology: An International Journal. 3(1): 17-26, 2015

Damien Cullington, Kevin M. Goode, Jufen Zhang, John G.F. Cleland, Andrew L. Clark. Is Heart Rate Important for Patients With Heart Failure in Atrial Fibrillation? JACC Heart Failure. 2014; 2(3):213-220

J Zhang, R Dierckx, JG Cleland. “Xanthine Oxidase Inhibition for the Treatment of Cardiovascular Disease: A Systematic Review and Meta-Analysis”. Cardiovascular Therapeutics. April 2014, volume 32, issue 2, pages 57–58

Pellicori P, Kallvikbacka-Bennett A, Zhang J, Khaleva O, Andrew L. Clark, John G. F. Cleland, J, Warden. Revisiting a classical clinical sign: jugular venous ultrasound. Int J Cardiol. 2014 Jan 1; 170(3):364-70

Pellicori P, Kallvikbacka-Bennett A, Khaleva O, Carubelli V, Costanzo P, Castiello T, Wong K, Zhang J, Cleland JG, Clark AL. Global longitudinal strain in patients with suspected heart failure and a normal ejection fraction: does it improve diagnosis and risk stratification? Int J Cardiovasc Imaging. 2014 Jan;30(1):69-79

J. Zhang, K.M. Goode, A.S. Rigby, Balk AH, J.G.F. Cleland, Identifying patients at risk of death or hospitalisation due to worsening heart failure using decision tree analysis: Evidence from Trans-European Network-Home-Care Management System (TEN-HMS) Study. International Journal of Cardiology (2013) 163(2): 149-56

Pierpaolo Pellicori, Valentina Carubelli, Jufen Zhang, Teresa Castiell, Nasser Sherwi, Andrew L. Clark, John G. F. Cleland, IVC Diameter in Patients With Chronic Heart Failure. Relationships and Prognostic Significance. JACC: Cardiovascular Imaging, 2013 Jan; 6(1):16-28 – 2012 Young Author Achievement Award for JACC Cardiovascular Imaging

Thibaud Damy, Anna Kallvikbacka-Bennett, Jufen Zhang, Kevin Goode, Laszlo Buga, James Hobkirk, Ashraf Yassin, Jean-Luc Dubois-Rande, Luc Hittinger, John G. F. Cleland, Andrew L. Clark, Does the physical examination still have a role in patients with suspected heart failure? European Journal of Heart Failure (2011), volume 13, 1340-1348

Zhang J, Goode KM, Cuddihy P, Cleland JG, Predicting hospitalisation due to worsening heart failure using daily weight measurement: An analysis of the Trans-European Network-Home-Care Management System (TEM-HMS) Study. European Journal of Heart Failure (2009) 11, 420-427

Alan S Rigby, Jufen Zhang and Kevin M Goode, Statistical Methods in Epidemiology. IX. Survival (Failure-time) Models. Disability and Rehabilitation, 2009; 1–6

Yahya Al-Najjar, Kevin M. Goode, Jufen Zhang, John G.F. Cleland and Andrew L. Clark, Red cell distribution width: an inexpensive and powerful prognostic marker in heart failure. European Journal of Heart Failure (2009) 11, 1155-1162

John G.F. Cleland, Azam Torabi, Jufen Zhang, and Raj K. Chelliah, Chapter: Medical therapy for chronic heart failure, 43: Antithrombotic agents, Oxford Textbook of Heart Failure. 978-0-19-957772-9 | Hardback | July 2011

Recent presentations and conferences

The factors associated with heart failure hospitalization rates in heart failure patients with normal and reduced left ventricular ejection fraction. ESC Heart Failure congress 2016

Predicting Survival in Patients with Heart Failure Based on Variables Used in the MAGGIC model. The European Society of Cardiology (ESC) Heart Failure 2015

Dynamic prediction using joint models in patients with suspected heart failure. Statisticians in the Pharmaceutical Industry 2014 Conference

Factors associated with quality of life in patients with suspected heart failure. The European Society of Cardiology (ESC) Heart Failure 2013

Mortality risk stratification in chronic heart failure patients: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). The ESC Congress 2012