Dr Christina Greenwood

Senior Research Fellow (Postgraduate Medical Institute)

Faculty:Faculty of Medical Science

Location: Chelmsford

Areas of Expertise: Molecular diagnostics

Research interests lie in molecular diagnostics and stratified medicine in the field of cancer biomarkers. Specialism in breast and colorectal cancer cell signalling, protein interactions (proteomics) and gene expression with an emphasis on translational medicine

Email: christina.greenwood@anglia.ac.uk


Dr Chrissy Greenwood obtained her PhD from Cambridge University in infective immunology where she was a Harrison Watson Junior Fellow. She joined Anglia Ruskin University in 2006 as a Research Fellow. She spent some time working on a collaborative project as a Senior Post Doctorial Fellow at the Karolinska Institute, Stockholm, Sweden (2009). She is now a Senior Research Fellow in the Molecular and Cellular Biology laboratory based in the Postgraduate Medical Institute.

Chrissy’s Research has focused on identifying markers that may predict metastasis and response to neoadjuvant chemotherapy in breast cancer patients. She now concentrates on molecular diagnostics for cancer biomarkers. Chrissy also has an interest in holistic approach to cancer management for breast cancer patients with a specific focus on stress.

She maintains long running collaborations with senior researchers at Essex University (proteomics and breast cancer, Karolinska Institute (proteomics) and Imperial University, London (nanoparticles and targeted therapeutics for breast cancer). She has significant experience in translational clinical research and the use of human tissues in research working closely with clinicians in hospitals and pathology departments.

Chrissy is also involved in delivering training courses to PhD/Early career researchers (ECR) and has experience in lecturing at both undergraduate and postgraduate level. She currently supervises 5 MD/PhD students.

Research interests

  • Cancer biology
  • Translational clinical research ("bench to beside").
  • Proteomics.
  • Nanoparticles as novel therapeutics for targeting breast cancer
  • Molecular diagnostics
  • Stress and disease- modulation of stress during cancer diagnosis for improved patient benefit

Areas of research supervision

PhD Supervision

  • Okezie Ofor. Characterisation of novel protein partners of the CCTC- binding factor in breast cancer cell lines. PhD Candidate, Anglia Ruskin University (First Supervisor (2010-).
  • Mya Fekry. Identification and characterisation of renal injury/cytotoxicity as a result of MDPV exposure. Part time PhD Candidate, Anglia Ruskin University (First Supervisor (2010- ).
  • Harvinder Singh. Use of Proximity ligation assay in the detection of C.difficile infections. PhD Candidate, Anglia Ruskin University (Second Supervisor (2012- ).
  • Basmah Othman.  Breast cancer targeting using ZnO Nanoparticles. Completed. PhD Candidate. Imperial College, London. (Advisor 2012-2014)
  • Whitney Chow. Use of tranexamic acid and Peak plasma blade in DIEP/MS-TRMA breast reconstruction MD candidate (Second Supervisor 2014-)
  • You Yone. Molecular biomarkers to predict response to Avastin and XELOX therapy in metastatic Colorectal Cancer (mCRC). MD candidate (First Supervisor 2015-)


  • PhD Infective Immunology Cambridge University
  • BSc (Dual Hons) Keele University

Memberships, editorial boards

  • Practitioner in Clinical Reflexology (since 2007) (Institute of Complementary Medicine)

Research grants, consultancy, knowledge exchange

  • Researcher Links Initiative: Reviewer of British Council funding; ECR Workshop and Travel Grants (2013-2015)
  • External scientific reviewer for Grant Applications. RfpB (NIHR) (2012)

Selected recent publications

Bustin, S., Dhillon, H., Kirvell, S., Greenwood, C., Shipley, G.L. and Nolan, T. (2015). Variability of the reverse transcription step: practical implications. Clinical Chemistry, 16:1.

McVicar A, Ravalier JM & Greenwood C. (2013). Biology of Stress Revisited: Intracellular Mechanisms and the Conceptualization of Stress. Stress Health. e-publication

Metodieva G, Nogueira-de-Souza NC, Greenwood C, Al-janabi K, lengs L, Bucalas R, Metodiev M. (2013). CD74-dependent Deregulation of the Tumor Suppressor Scribble in Human Epithelial and Breast Cancer Cells. Neoplasia. 15 (6) pp660-668

Greenwood C, Gergana Metodieva, Khalid Al-Janabi, Berthold Lausen, Louise Alldridge, Lin Leng, Richard Bucala, Nelson Fernandez, and Metodi V. Metodiev. (2012). Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node  metastasis in triple-negative breast cancer  J Proteomics. 75 (10) pp 3031-40.

Zakharchenko O, Greenwood C, Lewandowska A, Hellman U, Alldridge L, Souchelnytskyi S. (2011). Meta-data analysis as a strategy to evaluate individual and common features of proteomic changes in breast cancer. Cancer Genomics Proteomics. Jan-Feb;8(1):1-14.

Olena Zakharchenko,Christina Greenwood, Louise Alldridge and Serhiy Souchelnytskyi. (2011). Optimized Protocol for Protein Extraction from the Breast Tissue that is Compatible with Two-Dimensional Gel Electrophoresis. Breast Cancer: Basic and Clinical Research: March, 5 37-42

Recent presentations and conferences

Greenwood C. (2014) Stress outcomes and cortisol responses in breast cancer patients receiving reflexology: A pilot randomised controlled trial. CAMSTRAND Conference. June .Christie NHS Foundation Trust, Manchester.

Greenwood C. (2013) Anxiety, cortisol and the effects of reflexology on breast cancer patients. CAMSTRAND Conference. July. University of Westminster

Greenwood, C. (2010). Identification of phosphoproteins involved in neoadjuvant chemotherapy responsiveness of breast tumours using proteomics. Essex Biomedical Sciences Institute (EBSI), First Annual Conference, Colchester Hospital, Essex, United Kingdom, 14th April.

Greenwood, C. (2009). Identification of phosphoproteins involved in primary chemotherapy responsiveness of breast tumours using proteomics. Cancer Center Karolinska workshop-retreat, Stockholm, Sweden, 27 August.

Greenwood, C. (2009). Evaluation of anxiety, salivary cortisol and melatonin secretion following reflexology treatment: A pilot study in healthy individuals. Focus on Methodology and Lessons Learned. CAMSTRAND Annual Conference, Middlesex University, Hendon Campus, London, United Kingdom, 30th April.