Our Biomedical Research Group (BRG) aims to integrate research into the genotypic and phenotypic relationships underpinning our understanding of health, disease and ageing in human, animal and microbial systems.
Our research interests involve biochemical and molecular mechanisms that underpin the pathogenesis and aetiology of mammalian diseases, such as rheumatoid arthritis, myeloproliferative diseases, and tumorigenesis; metabolic factors associated with human disease and exercise; the genetics of antibiotic resistance in bacteria; and bacterial pathogen virulence and evolution.
Here is a list of the current research interests of the group along with the academic contact:
Dr Claire Pike - Cancer, Molecular Biology, Molecular Genetics, Epigenetics
Dr Peter Coussons - Transglutaminase enzymes, Cancer, Antioxidants, Catalytic antibodies, Erythropoietin and rheumatoid arthritis
Dr Richard Jones - Macular degeneration
Dr Havovi Chichger - Vascular disease and diabetes
Dr Linda King - Lipotoxicity and impairment of insulin signalling in type II diabetes
Dr Nicholas Pugh - Platelet signalling pathways
Dr Grisha Pirianov - Regulation of the inflammatory response, proinflammatory mediators, tol-like receptors, anti-inflammatory drugs