Dr Mari L. Uchimoto

Lecturer

Faculty:Faculty of Science & Technology

Department:Biomedical and Forensic Science

Location: Cambridge

Mari's experience and expertise lie in the area of forensic genetics.

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mari.uchimoto@anglia.ac.uk

Background

Mari obtained her MSci and Ph.D. degree from the University of Huddersfield. Her experience and expertise lie in the area of forensic genetics. Her Ph.D. research focused on developing a microRNA body fluid identification test for use in forensic casework. Mari has also performed research at the University of Virginia. Her work focused on developing forensic and clinical protocols for use on lab-on-a-chip technologies. Her current research interests include DNA methylation and RNA stability.

Research interests

  • MicroRNA analysis
  • Messenger RNA analysis
  • DNA methylation

Qualifications

  • Ph.D. in Forensic Genetics
  • MSci. in Forensic and Analytical Science

Memberships, editorial boards

Mari is a member of the International Society of Forensic Genetics.

Selected recent publications

Uchimoto M.L., Beasley E., Coult N., Omelia E.J., World D., Williams G. (2013) Considering the effect of stem-loop reverse transcription and quantitative PCR analysis of blood and saliva specific microRNA markers upon mixed body fluid stains. Forensic Science International: Genetics 7(4) 418-421.

Williams G., Uchimoto M.L., Coult N., World D., Beasley E. (2013) Body fluid mixtures; resolution using forensic microRNA analysis. Forensic Science International: Genetics Supplement Series 4(1) 292-293.

Williams G., Uchimoto M.L., Coult N., World D., Beasley E., Avenell P. (2013) Characterisation of body fluid specific microRNA markers by capillary electrophoresis. Forensic Science International: Genetics Supplement Series 4(1) 274-275.

Omelia E.J., Uchimoto M.L., Williams, G. (2013) Quantitative PCR analysis of blood- and saliva-specific microRNA markers following solid-phase DNA extraction. Analytical Biochemistry 435(2) 120-122.

Van der Meer D., Uchimoto M.L., Williams G. (2013) Simultaneous analysis of microRNA and DNA for determining the body fluid origin of DNA profiles. Journal of Forensic Sciences 58(4) 967-971.

Hagan K.A., Reedy C.R., Uchimoto M.L., Basu D., Engel D.A., Landers. J.P. (2011) An integrated, valveless system for microfluidic purification and reverse transcription-PCR amplification of RNA for detection of infectious agents. Lab on a Chip 11(5) 957-961.

Recent presentations and conferences

Uchimoto M.L., Coult N., Williams G. (2014) Characterisation of miR-205, miR-451 and RNU44 in blood and saliva samples. International Society for Forensic Genetics English Speaking Working Group Annual Meeting. Athens, Greece.

Williams G., Uchimoto M.L., Coult N., Beasley E., World D., Avenell P. (2013) Capillary electrophoretic analysis of body fluid specific microRNA markers in order to multiplex with STR kits. European Forensic DNA Working Group Meeting. Lisbon, Portugal.

Uchimoto M.L., van der Meer D., Williams G. (2012) Single Channel Simultaneous Analysis of DNA and MicroRNA. Australian and New Zealand International Symposium. Hobart, Tasmania, Australia.

Uchimoto M.L., Coult N., Williams G. (2012) A co-extraction method for DNA and mRNA for use in forensic casework. Australian and New Zealand International Symposium. Hobart, Tasmania, Australia.

Uchimoto M.L., Van der Meer D., Williams G. (2012) Single channel simultaneous analysis of DNA and MicroRNA. American Academy of Forensic Sciences Conference. Atlanta, GA, USA.

Uchimoto M.L., Williams G. (2011) A novel method for the simultaneous co-isolation of DNA and mRNA for forensic casework samples. Forensic Research and Teaching Conference. Nottingham, UK.

Uchimoto M.L., Landers J.P. (2010) Optimizing an RT PCR method for integration on a microfluidic system. Royal Society of Chemistry Conference. Huddersfield, UK.

Uchimoto M.L., Hagan K.A., Landers J.P. (2009) Development of a microfluidic system for RNA analysis. American Chemical Society Conference. Charlottesville, VA, USA.

Hagan K.A., Uchimoto M.L., Dewald A.H., Landers J.P. (2009) Towards a microfluidic device for integrated purification and amplification. American Academy of Forensic Sciences Conference. Denver, CO, USA.

Awards

Best Oral Presentation in Biological Criminalistics at the Australian and New Zealand International Symposium (2012), Hobart, Tasmania, Australia

Media experience

Return of the Black Death. Channel 4 documentary, 6 April 2014