Dr Caray A Walker


Faculty:Faculty of Science & Technology

Department:Biomedical and Forensic Science

Location: Cambridge

Areas of Expertise: Life sciences

Caray is a lecturer in microbiology and her primary research interests are in the pathogenesis of important bacterial animal pathogens and in particular zoonoses.

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Caray’s research focuses on the mechanisms used by these bacteria to establish infection. Particular emphasis is on how environmental factors, such as iron, regulate gene expression and the importance of these mechanisms in the infection process. How these mechanisms can be exploited for use as novel vaccines and diagnostic test candidates is also a feature of her research.

Caray has a particular interest in Corynebacterium, Streptococcus and Mycoplasma genera of bacteria. The genus Corynebacterium includes several pathogens for example: Corynebacterium diphtheriae (the causative agent of diphtheria), Corynebacterium ulcerans (an emerging zoonotic pathogen) and Corynebacterium pseudotuberculosis (causative agent of caseous lymphadenitis in livestock, as well as ulcerative lymphangitis in horses and lymphadenitis in humans). Of the Streptococcus and Mycoplasma genera Caray’s research is focussed on the important animal pathogens S. suis, S. equi subsp zooepidemicus (both zoonoses) and Mycoplasma cynos (a pathogen of dogs).

Research interests

  • Pathogenesis of bacterial diseases of animals, particularly zoonoses.
  • Modulation of gene expression by environmental factors such as iron.
  • Identification of putative virulence genes
  • Virulence gene mutagenesis
  • Infection models
  • Vaccinology
  • Prevalence of new and emerging bacterial pathogens of animals, in particular zoonoses

Areas of research supervision

  • PhD supervisor – Project entitled: Analysis of the DtxR global regulon of Corynebacterium pseudotuberculosis


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BSc (Hons) Biomedical Sciences
Caray is module leader for Microbial Pathogenicity and General Microbiology


  • PhD Molecular Bacteriology, University of Glasgow and Moredun Research Institute
  • MSc by Research in Veterinary Diagnostics, University of Edinburgh
  • BSc (Hons) Biological Sciences, University of Plymouth

Memberships, editorial boards

  • Member of Society of General Microbiology
  • Member of American Society of Microbiology

Selected recent publications

Priestnall, S.L. Mitchell, J.A. Walker, C.A, Erles, K. and Brownlie, J., 2014. New and Emerging Pathogens in Canine Infectious Respiratory Disease. Veterinary Pathology, Mar:51(2), pp.492-504.

Walker, C.A. Mannering, S.A. Shields, S. Blake D.P. and Brownlie J., 2013. Complete Genome Sequence of Mycoplasma cynos strain C142. Genome Announcements, Jan: 1(1). pii: e00196-12.

Walker, C.A. Donachie, W., Smith, D.G.E and Fontaine, M.C., 2011. Targeted allele-replacement mutagenesis of Corynebacterium pseudotuberculosis. Applied and Environmental Microbiology, 77(10), pp.3532-5.

May, J.P., Walker, C.A. Maskell, D.J. and Slater, J.D., 2004. Development of an in vivo Himar1 transposon mutagenesis system for use in Streptococcus equi subsp. equi. FEMS Microbiology Letters, 238, pp.401-409.