Director of Studies - Cambridge

Contact Details:
Location: Cambridge Bryant 105
Tel No: +44 (0)845 196 2746
Fax No: +44 (0)1223 417712
Email: leigh.stoeber@anglia.ac.uk

Research Interests

Cell cycle and cyclin expression
Histopathology of normal and neoplastic human tissues
Tumour biology
Chromosomal replication and origin licensing
Mammalian cell synchronisation
Gravitational biology.

Publications

Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer. Loddo M, Kingsbury SR, Rashid M, Proctor I, Holt C, Young J, El-Sheikh S, Falzon M, Eward KL, Prevost T, Sainsbury R, Stoeber K, Williams GH. Br J Cancer. 2009 Mar 24;100(6):959-70. Epub 2009 Feb 24.

DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma. Kulkarni AA, Loddo M, Leo E, Rashid M, Eward KL, Fanshawe TR, Butcher J, Frost A, Ledermann JA, Williams GH, Stoeber K. Clin Cancer Res. 2007 Oct 15;13(20):6153-61.

Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells. Okuyama M, Laman H, Kingsbury SR, Visintin C, Leo E, Eward KL, Stoeber K, Boshoff C, Williams GH, Selwood DL. Nat Methods. 2007 Feb;4(2):153-9. Epub 2007 Jan 14.

DNA replication licensing in peripheral B-cell lymphoma. Obermann EC, Eward KL, Dogan A, Paul EA, Loddo M, Munson P, Williams GH, Stoeber K. J Pathol. 2005 Feb;205(3):318-28.

Obermann, E.C., Eward, K.L., Dogan, A., Paul, E.A., Loddo, M., Munson, P., Williams, G.H., Stoeber, K. DNA Replication Licensing in Peripheral B-cell Lymphoma. Journal of Pathology. In Press. December, 2004.

Eward, K.L., Obermann, E.C., Shreeram, S., Loddo, M., Fanshawe, T., Williams, C., Jung, H., Prevost, A.T., Blow, J.J., Stoeber, K., Williams, G.H. DNA Replication Licensing in Somatic and Germ Cells. Journal of Cell Science. November, 2004.

Wharton, S.B., Hibberd, S., Eward, K.L., Crimmins, D., Jellinek, D.A., Levy, D., Stoeber, K., Williams, G.H. DNA Replication Licensing and Cell Cycle Kinetics of Oligodendroglial Tumours. British Journal of Cancer. 2004 July; 91(2):262-9.

Grover, N.B., Eward, K.L. and Helmstetter, C.E. Synchronous Cultures from the Baby Machine; A Model for Animal Cells. Mathematical Biosciences. 2004 July; 190(1):87-96.

Eward, K.L., Van Ert, M.N., Thornton, M. and Helmstetter, C.E. Cyclin mRNA Stability does not vary during the Cell Cycle of Minimally Disturbed Synchronous MOLT-4 cells. Cell Cycle. 2004. August; 3(8).

Helmstetter, C.E., Thornton, M., Romero, A. and Eward, K.L. Synchrony in Human, Mouse and Bacterial Cell Cultures- A Comparison. Cell Cycle. 2003. Jan-Feb; 2(1): 42-5.

Thornton, M., Eward, K.L. and Helmstetter, C.E. Production of Minimally Disturbed Synchronous Cultures of Hematopoietic Cells. Biotechniques. May 2002.