Professor Michael Cole BA (Hons) Cantab., PhD (London)

Professor Mike Cole

Director of Research, Knowledge Transfer and Scholarship & Acting Head of Life Sciences

Contact details

Office: Room Cos 312a
Tel: +44 (0)1223 363271 (ext 2525)
Fax: +44 (0)1223 417712
Email: michael.cole@anglia.ac.uk

Profile

Professor Cole graduated from the University of Cambridge in 1986 having read Natural Sciences. He then became the first PhD bursary student supported by the Royal Botanic Gardens, Kew, where he developed his interest in phytochemicals and natural products as potential agrochemicals and pharmaceuticals. Having worked with colleagues at both Birkbeck College and Imperial College, University of London, Professor Cole obtained his PhD in Natural Product Chemistry in 1990.

Following a short spell in industry, Professor Cole joined the Forensic Science Unit at the University of Strathclyde in 1991 as a short course tutor. In this position he developed CPD and research courses in forensic chemistry and delivered them as far afield as North and South America, Asia and many countries in Europe. Following permanent appointment at Strathclyde, and progressing through lecturing and senior lecturing posts, he became the Reader of Forensic Science and Director of the Forensic Science Unit in 2000.

In 2001, Professor Cole joined what is now Anglia Ruskin University as Professor of Forensic Science and Head of the Department of Forensic Science. At the time he was the youngest full Professor of Forensic Science in the world. Following the merger of the Departments of Life Science and Forensic Sciences and leading the new Department, Professor Cole became Director of Research, Knowledge Transfer and Scholarship for the Faculty of Science and Technology in April, 2010.

Research interests

Professor Cole has a longstanding research interest in natural products and in drug chemistry. He led a European Consortium, funded under the EU Framework V programme, to develop a harmonised method for the profiling of amphetamines. The result of this work is a method that is now used all over the world. At present his research interests lie in development of analytical techniques for the newly controlled and recently developed amphetamine type stimulants and an investigation of the degree and mechanisms of toxicity of the drugs and their impurities. The former work has been widely published and presented in the USA, Europe and in Asia. The latter newer work on drug toxicity has been the subject of broadcasts by the BBC television, local radio stations and has been subject of articles in the journal "Nature" and "Chemistry World" along with numerous newspaper reports and is currently being published.

Along with colleagues Professor Cole supervises a number of Ph.D. students. Chipo Kuleya (supervised with Dr. Sarah Hall) is developing a method for the chemical characterisation and chemical impurity profiling of phenylpiperazines. In the second year of her Ph.D., Chipo has presented at internal and external conferences and is on the point of publishing her work. More recently, Mya Fekry (supervised with Dr. Beverley Vaughan) has joined the group and is studying the toxicity of amphetamines, ring substituted amphetamines and new ATS type drugs. Some of this work has already been presented at international meetings. Joining the group Alex Turner (supervised with Dr. Lata Gautam and Colleen Moore) will be developing optimised methods for the profiling of other ATS drugs and looking at the time course of drug use.

There is also overseas interest in this research. For example, an Erasmus Bilateral Exchange Programme has been set up with the Jagellonian University in Krakow with a graduate student, and staff, exchange programme currently running. Further links are being developed with the University of Maastricht in the Netherlands. A strong research relationship is also being developed with Pavlodar State University in Kazakhstan.

Selected publications

Scientific papers since 2000

M.D. Cole. (2000) The analysis of Cannabis by SFC with UV detection. Methods in Biotechnology. 13, 145 - 149.

J.C.I. Lee, M.D. Cole and A. Linacre (2000) Identification of hallucinogenic fungi by a genus specific DNA test. Forensic Science International 112, 123 - 133.

J.C.I. Lee, M.D. Cole and A. Linacre (2000) Identification of hallucinogenic fungi from the genera Psilocybe and Panaeolus, by Amplified Fragment Length Polymorphism (AFLP). Electrophoresis 21, 1484 - 1487.

Ballany J, Caddy B, Cole M, Finnon Y, Aalberg L, Janhunen K, Sippola E, Andersson K, Bertler C, Dahlén J, Kopp I, Dujourdy L, Lock E, Margot P, Huizer H, Poortman A, Kaa E, Lopes, A. (2001) Development of a harmonised pan-European method for the profiling of amphetamines. Science and Justice 41, 193 - 196.

R.J. McCurdy, T. Atwell and M.D. Cole (2001) The use of vapour phase ultra-violet spectroscopy for the analysis of arson accelerants in fire scene debris. Forensic Science International 123, 191 - 201.

Chaseling, J., Cole, M.D., Lee, J.C.I. and Linacre, A.M.T. (2001) Identification and comparison of fungal drugs. Problems of Forensic Sciences 96, 127 - 130.

Linacre, A., Cole, M., Hunt, A., Nic Daeid, N., Thorpe, J, Watson, N. and White, P. (2001) Training in the Forensic Sciences. Problems of Forensic Sciences 96, 165 - 167.

Magora, B.H. and Cole, M.D. (2001) Phytochemical and toxicological studies of some traditional Botswanan plants used in traditional medicine. Problems of Forensic Sciences 97, 358 - 362.

A. Linacre, M. Cole and J. Chun - I Lee (2002) Identifying the presence of "magic mushrooms" by DNA profiling. Science and Justice 42, 50 - 54.

Cole, M.D. and Linacre, A.M.T. (2002) The identification of controlled plant drugs using phytochemistry and DNA. Current Topics in Phytochemistry 5, 129 - 140.

Cole, M.D., Lea, C. and Oxley, N. (2002) 4-Bromo-2,5-dimethoxyphenethylamine (2-CB) : a review of the public domain literature. Science and Justice 42, 223 - 224.

Magora, B.H., Gray, A.I., Cole, M.D. and Rahman, M. M. (2003) Swertiamarin from Enicostemma axillare (Gentianaceae). Biochemical Systematics and Ecology 31, 553 - 555.

Linacre, A., Cole, M. and Magora, B. (2003) DNA typing of plants used in traditional medicines. Forensic Science International 136, 68 - 69.

Kelly, J., Carter, T. and Cole, M.D. (2003) Forensic identification of non human mammals involved in the bushmeat trade using restriction digests of PCR amplified mitochondrial DNA. Forensic Science International 136, 379 - 380.

Aalberg, L., Anderson, K., Bertler, C., Borén, H., Cole, M.D., Dahlén, J., Finnon, Y., Huizer, H., Jalava, K., Kaa, E., Lock, E., Lopes, A., Margot, P., Poortman, A. and Sippola, E. (2005) Development of a harmonised method for the profiling of amphetamines I Synthesis of standards and compilation of analytical data. Forensic Science International. 149, 219 - 229.

Aahlberg, L., Andersson, K., Bertler, C., Cole, M.D., Dahlén, J., Finnon, Y., Huizer, H., Jalava, K., Kaa, E., Lock, E., Lopes, A., Poortman-van der Meer, A. and Sippola, E. (2005) Development of a harmonised method for the profiling of amphetamines II. Stability of impurities in organic solvents. Forensic Science International. 149, 231 - 241.

Gautam, L., Scott, K.S. and Cole, M.D. (2005) Amphetamine binding to synthetic melanin and Scatchard analysis of binding data. J. Anal. Toxicol 29, 339 - 341.

Andersson K., Jalava K., Lock E., Aalberg L., Finnon Y., Huizer H., Kaa E., Lopes A., Poortman-van der Meer A., Cole M.D., Dahlén J., and Sippola E. (2007) Development of a harmonised method for the profiling of amphetamines, III. Development of the gas chromatographic method. Forensic Science International 169, 50 - 63.

Andersson K., Jalava K., Lock E., Finnon Y., Stevenson S., Aalberg L., Huizer H., Kaa E., Lopes A., Poortman-van der Meer A., Cole M.D., Dahlén J., Sippola E. (2007) Development of a harmonised method for the profiling of amphetamines IV. Optimisation of sample preparation. Forensic Science International 169, 64 - 76.

Lock E. Aalberg L., Andersson K., Dahlén J., Cole M.D., Finnon Y., Huizer H., Jalava K., Kaa E., Lopes A., Poortman A., and Sippola E. (2007) Development of a harmonised method for the profiling of amphetamine V. Determination of the variability of the optimised method. Forensic Science International 169, 77 - 85.

Williamson, J.M. and Cole, M.D. (2007) A review of the illegal trade and identification of endangered species of Southeast Asian marine turtles and tortoises. Global Forensic Science Today. Issue 3, pp. 2 - 15.

Gautam, L. Scott, K.S., Emmett, T.F. and Cole, M.D. (2008) Characterisation of natural and synthetic melanins. Global Forensic Science Today. Issue 6, pp. 27 - 43.

Edmonds-Smith, E.S., Lawther, G. and Cole, M.D. (2008) Analysis of piperazines by high performance liquid chromatography. Global Forensic Sciences Today. Issue 7, pp. 14 - 22.

Al Haddad, A., White P.C. and Cole, M.D. (2009) Examination of a collection of Arabic Signatures. Journal of the American Society of Questioned Document Examiners 12, 35 - 53.

Vaughan, B.R., Gautam, L. and Cole, M.D. (2010) Solvent cytotoxicity in cell based assays fir in vitro drug toxicity screening. TIAFT Bulletin 40 Issue 2, pp. 14 - 18.

Nevison, C.M., Hughes, A. and Cole, M.D. (2011) Variability in lower leg aids used to achieve gait transitions on a dressage simulator. Journal of Veterinary Behaviour 6, 294.

Cole, M. and Caan, W. (2011) "To boldly go" : a model statistics course for doctoral training units. Nurse Researcher 19, 44 - 45.

Caan, W. and Cole, M. (2012) How much doctoral research on clinical topics is published? Evidence-Based Medicine 17, 71 - 74. doi:10.1136/ebmed-2011-100227.

Holman, S.W., Emmett, T.F. and Cole, M.D. (2012) A quantitative assessment of the chemical variation in food grade polyethylene cling film, a common wrapping material for illicit drugs, using attenuated total reflection-Fourier transform infrared spectroscopy. Analytical Methods 4, 1667 - 1673. doi: 10.1039/C2AY05889H.

Gautam, L., Shanmuganathan, A. and Cole, M.D. (2013) The forensic analysis of cathinones. Forensic Science Review. 25, 47 - 64.

Sanaei, A., Toulson, E.R. and Cole, M.D. (2012) Tuning and optimisation of an electronic network frequency extraction algorithm. Journal of the Audio Engineering Society. Submitted.

Greig, A., Cole, M. and Khudiyeva, S. (2013) Recommendations for change to achieve sustainable higher education in Kazakhstan. Journal of Education for sustainable development. Submitted.

Mwenesengole, E., Hall, S., Gautam, L., Waterhouse, J.S. and Cole, M. (2013) Simultaneous detection of controlled substances in waste water. Analytical methods. Submitted.

Other scientific output

Williamson, J.M. and Cole, M.D. (2007) A review of the illegal trade and identification of endangered species of Southeast Asian marine turtles and tortoises. Global Forensic Science Today. Issue 3, pp. 2 - 15.

Gautam, L. Scott, K.S., Emmett, T.F. and Cole, M.D. (2008) Characterisation of natural and synthetic melanins. Global Forensic Science Today. Issue 6, pp. 27 - 43.

Edmonds-Smith, E.S., Lawther, G. and Cole, M.D. (2008) Analysis of piperazines by high performance liquid chromatography. Global Forensic Sciences Today. Issue 7, pp. 14 - 22.

Vaughan, B.R., Gautam, L. and Cole, M.D. (2010) Solvent cytotoxicity in cell based assays fir in vitro drug toxicity screening. TIAFT Bulletin 40 Issue 2, pp. 14 - 18.

Cole, M.D. (2011) Poison in party pills is too much to swallow. Nature 474, 253. doi:10.1038/474253a

Cole, M. (2012) The case for a professional doctorate in forensic science. Forensic Magazine..

Gautam, L. and Cole, M.D. (2013) Drink Speaks the Truth : Forensic Investigation of Drug Facilitated Sexual Assaults. Forensic Magazine. In press.

News based output


Cole, M. (2008) Anglia Ruskin University - Short Courses in Forensic Science. Public Servant, April 2008, p 16.

Cole, M.D. and Bond, M. (2009) New Equine Degree. East Anglian Rider, April 2009, p. 29.

Hughes, D. and Cole, M. (2009) What forensic science can do to help the police. Public Servant, June 2009, p 44.

Cole, M.D. (2009) Anglia Equine Consultancy Launched. East Anglian Rider, July 2009.

Work featured in "Ecstasy substitute poses major health risks". Chemistry World.

Work featured in "Chemists in the shadow" by Adam Piore. Discover Magazine. March 2012, 36 - 43.
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