Dr Linda King, PhD
Lecturer in Biomedical Science
Location: Dav 001, CambridgeTel No:+44 (0)1223 363271 (ext. 2207)
Fax No: +44 (0)1223 417712
Email: Linda.king@anglia.ac.uk
Teaching experience
Linda has been teaching a number of subjects at both the University of Cambridge and Anglia Ruskin University for the past five years, including cell biology, biochemistry and physiology. She is now module leader for Human Anatomy and Physiology 1 and 2, and Physiology of Organ Systems and also contributes teaching to a number of other modules.Research interests
G-protein coupled receptors - transcription, movement through the endomembrane system and action at the cell membrane, using the melanocortin 1 receptor as a model of function.Metabolic changes in ischaemic heart disease and diabetes.
Publications
Desrois M, Sidell RJ, Gauguier D, King LM, Radda GK, Clarke K. Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart. Cardiovasc Res 2004, 61:288-296.L. M. King, R. J. Sidell, J. R. Wilding, G. K. Radda, and K. Clarke. Free fatty acids, but not ketone bodies, protect diabetic rat hearts during low-flow ischemia. Am J Physiol Heart Circ Physiol, March 1, 2001; 280(3): H1173 - H1181.
JCA Hopkins, Bia B, Crilley JG, Boehm EA, Sang EA, Tinsley JA, King LM, Radda GK, Davies KE, Clarke K. Muscular dystrophy: from gene to patient. Mag Res Mat Biol, Phys Med 2000, 11:7-9.
King LM, Sidell RJ, Jones BE, Radda GK, Clarke K. Fatty acids, ischaemic damage and the diabetic heart. Mag Res Mat Biol, Phys Med 1998, 6:173-174
Taegtmeyer H, King LM, Jones BE. Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy. Am J Cardiol 1998, 82 (Suppl 1):54K-60K
King LM, Opie LH. Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow. Cardiovasc Res 1998, 39:381-392
Desrois M, Sidell RJ, Gauguier D, King LM, Radda GK, Clarke K. Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart. Cardiovasc Res 2004, 61:288-296.
L. M. King, R. J. Sidell, J. R. Wilding, G. K. Radda, and K. Clarke. Free fatty acids, but not ketone bodies, protect diabetic rat hearts during low-flow ischemia. Am J Physiol Heart Circ Physiol, March 1, 2001; 280(3): H1173 - H1181.
JCA Hopkins, Bia B, Crilley JG, Boehm EA, Sang EA, Tinsley JA, King LM, Radda GK, Davies KE, Clarke K. Muscular dystrophy: from gene to patient. Mag Res Mat Biol, Phys Med 2000, 11:7-9.
King LM, Sidell RJ, Jones BE, Radda GK, Clarke K. Fatty acids, ischaemic damage and the diabetic heart. Mag Res Mat Biol, Phys Med 1998, 6:173-174
Taegtmeyer H, King LM, Jones BE. Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy. Am J Cardiol 1998, 82 (Suppl 1):54K-60K
King LM, Opie LH. Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow. Cardiovasc Res 1998, 39:381-392
Lochner A, Huisamen B, Klopper JF, Opie LH, King LM, Du Toit EF. Myocardial metabolism. Cardiovasc J S Afr 1997 (Suppl C45-C53)
King L M, Opie LH. Does preconditioning act by glycogen depletion in the isolated rat heart? J Mol Cell Cardiol 1996, 28:2305-2321
King LM, Opie LH. Preconditioning - a reappraisal of protection, Basic Res Cardiol 91:5-7, 1996.
King LM, Boucher FR, Opie LH. Coronary flown and glucose delivery as determinants of contracture in the ischaemic myocardium. J Mol Cell Cardiol 27:7-01-720, 1995.
Von Oppell UO, King LM, du Toit EF, Owen EP, Reichart B, Opie LH. Effect of pH shifts induced by oxygenating crystalloid cardioplegic solutions. Ann Thorac Surg 52 (4):903-907, 1991
Von Oppell UO, King LM, du Toit EF, Owen EP, Reichart B, Opie LH. Effect of oxygenation and consequent pH changes on the efficacy of St Thomas' Hospital cardioplegic solution. J Thorac Cardiovasc Surg 102:396-404, 1991.
Von Oppell UO, du Toit EF, King LM, Owen EP, Reichart B, Opie LH. St Thomas' Hospital cardioplegic solution. Beneficial effect of glucose and multidose reinfusions of cardioplegic solution. J Thorac Cardiovasc sSurg 102:405-412, 1991.
Coetzee WA, King LM. Electrophysiology of rat hearts and rabbit ventricular myocytes during reperfusion after transient ischaemia. In: Ionic currents and Ischaemia. Eds: J Vereecke, PP von Bogaert, F Verdonck, Leuven University Press, 1990, 285-287
Rabiner EA, Butkow N, King LM. Effect of electrical pacing and external calcium concentration on the contractile performance of the isolated perfused rat heart. S Afr J Sci 86:24-27, 1990.
Bonegio RGBm Driver HS, King LM, Laburn HP, Shapiro CM. Circadian temperature rhythm blunting and sleep composition. Acta Physiol Scand, 133 (Suppl 574);44-47, 1988.
Cowie RL, King LM. Pulmonary tuberculosis in corticosteroid-treated asthmatics. S Afr Med J, 72:849-850, 1987.
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