Professor Madhavan Rajan

Professor of ophthalmic and visual sciences

Mr Rajan qualified as medical doctor in 1994 and has 15 years experience in ophthalmology. He underwent specialist ophthalmic training in London and the South East. His interest in corneal refractive surgery led to a research fellowship focusing on corneal wound healing mechanisms in laser refractive surgery at St Thomas' Hospital, London. His research in the field of corneal surgery led to a MD degree at the University of London. Subsequently he underwent a 2-year corneal surgical fellowship at Moorfield's eye hospital, London where he acquired extensive experience in newer techniques in corneal transplantation and corneal research. He was appointed as corneal consultant in 2007 and currently is the lead clinician for cataract and corneal surgery at Addenbrooke's hospital.

Research Interests

• Corneal wound healing mechanisms
• Corneal transplantation - newer techniques and devices
• Corneal drug delivery
• Corneal stem cell research
• Corneal diagnostics

Consultancy and other Professional Activity

• Consultant ophthalmic surgeon and clinical lead, Cornea and cataract service, Addenbrooke's Hospital, Cambridge
• East of England representative for Ocular tissue advisory group (OTAG), NHS Blood & transplant, UK
• Member of UKISCRS, ESCRS and Royal college of Ophthalmologists, UK


Logan SA , Rajan MS , Graham E, Johnson EM and Klein JI., A case of aspergillus endophthalmitis in an immuncompetent woman: intraocular penetration of oral voriconazole. Cases Journal 2010, 3:31doi:10.1186/1757-1626-3-31

Daniel CS, Rajan MS, Saw VP, et al. Contact lens-related Fusarium keratitis in London and Ghent. Eye 2008.

Kashani S, Rajan M et al. Wavefront-Guided Retreatment After Primary Wavefront-Guided Laser In Situ Keratomileusis in Myopes and Hyperopes: Long-term Follow-up. Am J Ophthalmol 2008.

Rajan MS, Bunce C, Tuft S. Interocular axial length difference and age-related cataract. J Cataract Refract Surg 2008;34:76-9.

Shortt AJ, Secker GA, Rajan MS, et al. Ex vivo expansion and transplantation of limbal epithelial stem cells. Ophthalmology 2008;115:1989-97.
Tay E, Rajan MS, Saw VP, Dart JK. Dislocated intraocular lens into the vitreous cavity after DSAEK. J Cataract Refract Surg 2008;34:525-6.

Tay E, Rajan M, Tuft S. Listeria monocytogenes sclerokeratitis: a case report and literature review. Cornea 2008;27:947-9.

Rajan MS, O'Brart DP, Patmore A, Marshall J. Cellular effects of mitomycin-C on human corneas after photorefractive keratectomy. J Cataract Refract Surg 2006;32:1741-7.

Rajan MS, O'Brart D, Jaycock P, Marshall J. Effects of ablation diameter on long-term refractive stability and corneal transparency after photorefractive keratectomy. Ophthalmology 2006;113:1798-806.

Rajan MS, O'Brart DP, Patel P, et al. Topography-guided customized laser-assisted subepithelial keratectomy for the treatment of postkeratoplasty astigmatism. J Cataract Refract Surg 2006;32:949-57.
Rajan MS, Pantelidis P, Tong CY, et al. Diagnosis of Treponema pallidum in vitreous samples using real time polymerase chain reaction. Br J Ophthalmol 2006;90:647-8.

Jaycock PD, O'Brart DP, Rajan MS, Marshall J. 5-year follow-up of LASIK for hyperopia. Ophthalmology 2005;112:191-9.

Rajan MS, Watters W, Patmore A, Marshall J. In vitro human corneal model to investigate stromal epithelial interactions following refractive surgery. J Cataract Refract Surg 2005;31:1789-801.

Rajan MS, Jaycock P, O'Brart D, et al. A long-term study of photorefractive keratectomy; 12-year follow-up. Ophthalmology 2004;111:1813-24.

Rajan MS, Shafiei S, Mohrenfels CV, et al. Effect of exogenous keratinocyte growth factor on corneal epithelial migration after photorefractive keratectomy. J Cataract Refract Surg 2004;30:2200
Sobha S, Rajan MS, Jackson H. Choroidal neovascularization following hyperopic LASIK surgery. Clin Experiment Ophthalmol 2004;32:443-5.

Kielhorn I, Rajan MS, Tesha PM, et al. Clinical assessment of the Zeiss IOLMaster. J Cataract Refract Surg 2003;29:518-22.

Rajan MS, Syam P, Liu C. Systemic side effects of topical latanoprost. Eye 2003;17:442-4.

Barampouti F, Rajan M, Aclimandos W. Should active CMV retinitis in non-immunocompromised newborn babies be treated? Br J Ophthalmol 2002;86:248-9.

Dhanasekar G, Rajan MS, Nirmal KB, Watson SD. Focal myositis of the neck with idiopathic orbital myositis. J Laryngol Otol 2002;116:314-6.
Rajan MS, Keilhorn I, Bell JA. Partial coherence laser interferometry vs conventional ultrasound biometry in intraocular lens power calculations. Eye 2002;16:552-6.

Rajan MS, Bremner FD, Riordan-Eva P. Pupil perimetry in the diagnosis of functional visual field loss. J R Soc Med 2002;95:498-500.