Dr Mohammad Najlah

Principal Lecturer of Pharmaceutics and

Deputy Head of Department, Medicine and Healthcare Science

Faculty:Faculty of Medical Science

Location: Chelmsford

Areas of Expertise: Pharmaceutical science

Courses taught: Pharmaceutical Science, Pharmaceutical Science

Mohammad is a multidisciplinary pharmaceutical scientist with excellent experience of Pharmaceutical Higher Education as a teacher, researcher and strategic manager.

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Email: mohammad.najlah@anglia.ac.uk
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Background

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Mohammad took a pharmacy degree followed by postgraduate diploma (Industrial Pharmacy) at Damascus University and worked as a community pharmacist in Syria. He obtained his PhD (2007) from the University of Manchester, focusing on the ‘development of nano-medicines based on dendrimer prodrugs’. This research was continued at the University of Central Lancashire (UCLan) where he worked as a research fellow. During that period he also contributed in founding of the School of Pharmacy and Biomedical Sciences. In 2009 Mohammad joined the academic staff at the Faculty of Pharmacy, Al-Baath University where he took on senior roles including Acting Head of Pharmaceutics, Vice Dean for Students and Administrative Affairs until the end of 2013. Since joining Anglia Ruskin University, Mohammad has been instrumental in developing the SuperLabs Complex including the New Nano Tech Lab and the establishment of new undergraduate and postgraduate programmes.

Mohammad's research interests focus on the fabrication of multifunctional nanomedicines for drug delivery application. Three of his papers were listed as the most read articles in their respective journals and one appeared as the number one article in ScienceDirect’s TOP25 Hottest Article Listings. He also has active research collaborations in several UK and International Universities.

Research interests

  • Formulating nano-carrier delivery systems for targeting cancer stem cells
  • Polymeric prodrugs/conjugates and polymeric nano-particulates
  • Engineering novel nanomaterials for pharmaceutical and biomedical applications
  • Colloidal formulations (aerosols, nanoemulsions and nanodispersions)
  • Clinical pharmaceutics
  • Bioequivalence and in vivo/in vitro correlations

Teaching

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Qualifications

  • BPharm (Hons) in Pharmacy and Pharmaceutical Chemistry, Damascus University
  • Postgraduate Diploma (PgDip) in Industrial Pharmacy, Damascus University
  • PhD in Pharmaceutical Nanotechnology, School of Pharmacy, University of Manchester
  • University Certificate in Higher Education, University of Central Lancashire, UK

Memberships, editorial boards

  • The Royal Society of Chemistry-MRSC
  • The Royal Pharmaceutical Society
  • Fellow of the Higher Education Academy
  • American Association of Pharmaceutical Scientists (2005)
  • Controlled Released Society (2006)
  • Registered Pharmacist in Syria

Research grants, consultancy, knowledge exchange

  • Controlled Release Society Outstanding Oral Drug Delivery Award in 2006
  • Commendation for Outstanding Science, University of Central Lancashire (UCLan) in 2007

Selected recent publications

Peer-Reviewed Publications

Najlah, M., Kadam A., Wan, K.W., Ahmed, W., Taylor K. M.G., Elhissi,. (2016). A. Novel paclitaxel formulations solubilized by lipid nanoemulsions for brain tumour therapy. Int. J. Pharm., 506(1-2), 102-109.

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G., & Elhissi, A. (2016). A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502(1–2), 18-27

Rudokas, M., Najlah, M., Alhnan, M. A., & Elhissi, A. (2016). Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications. Med Princ Pract. PMID: 26938856

Aldalaty, A., Karam, A., Najlah, M., Khoder, M., Alany, R. (2016). Effect of non-cross-linked calcium on properties, swelling behaviour, drug release and mucoadhesiveness of calcium alginate beads. Carbohydr. Polym. 140, 163-170.

Tawari P., Wang Z., Najlah, M., Tsang C, Kannappan V, Liu P, Mcconville C, Armesilla A, Wang W. (2015). The cytotoxic mechanisms of Disulfiram and copper(II) in cancer cells. Toxicol. Res., 4, 1439-1442.

Najlah, M., Hidayat, K., Mwesigwa, E., Ahmed, W., Al-Obaidi, K., and Elhissi A. M. A. (2015). Facile approach to manufacturing non-ionic surfactant nanodipsersions. J. Liposome Res. 1-6.

Najlah, M., Parveen, I., Faheem, A., Ahmed, W., Phoenix A. D., Kevin Taylor M.G., and Elhissi, A. (2014). The effects of suspensions particle size on the performance of vibrating-mesh, air-jet and ultrasonic nebulizers. Int. J. Pharm., 461, 234-241.

Nasr, M., Najlah, M., D’Emanuele, A., and Elhissi, A. (2014). PAMAM Dendrimers as Aerosol Drug Nanocarriers for Pulmonary Delivery via Nebulization. Int. J. Pharm. 461, 242-250.

Kadam A., Najlah, M., Wan, K.W., Ahmed, W., Phoenix A. D., Kevin Taylor M.G., and Elhissi, A. (2013). Stability of parenteral nanoemulsions loaded with paclitaxel: the influence of lipid phase composition, drug concentration and storage temperature. Pharm. Dev. Tech. 19, 999-1004.

Najlah, M., Vali, A., Taylor, M., Arafat T. B., Ahmed, W., Phoenix A. D., Kevin Taylor M.G., and Elhissi, A. (2013). A study of the effects of sodium halides on the performance of air-jet and micropump mesh nebulizers. Int. J. Pharm. 456. 520-527.

Elhissi, A. M.A., Brar, J., Najlah, M., Roberts, S. A., Faheem, A. and Taylor, K. M.G. (2013). An ethanol-based proliposome technology for enhanced delivery and improved "respirability" of antiasthma aerosols generated using a Micropump vibrating-mesh nebulizer. J. Pharm. Tech. Res. 1, 171-180.

Teow, H.M., Zhou, Z., Najlah, M., Yusof, S.R., Abbott, N.J., and D’Emanuele, A. (2012). Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier. Int. J. Pharm. 441, 701-711.

Book Chapters

Najlah, M., Zhou, Z., and D'Emanuele, A., (2012). Dendrimer-Based Prodrugs: Synthesis and Biological Evaluation, Dendrimer-Based Drug Delivery Systems. John Wiley & Sons, Inc., pp. 157-206.

Conference Abstracts

Elhissi, A., Martin, G., Zhou, Z., Najlah, M., and D'Emanuele, A. (2010). Dendrimers as nanocarriers of a model steroid. UKICRS Symposium, Hertfordshire, United Kingdom.

Elhissi, A.M.A., Martin, G., Najlah, M., Zhou, Z., and D'Emanuele, A. (2010). Enhanced solubility of beclometasone dipropionate using G4 PAMAM dendrimers. J. Pharm. Pharmaco., 62; 10. 1267-1268.