Faculty:Faculty of Medical Science
Areas of Expertise: Molecular diagnostics
Research interests lie in molecular diagnostics and stratified medicine in the field of cancer biomarkers. Specialism in breast and colorectal cancer cell signalling, protein interactions (proteomics) and gene expression with an emphasis on translational medicine
Dr Chrissy Greenwood obtained her PhD from Cambridge University in infective immunology where she was a Harrison Watson Junior Fellow. She joined Anglia Ruskin University in 2006 as a Research Fellow. She spent some time working on a collaborative project as a Senior Post Doctorial Fellow at the Karolinska Institute, Stockholm, Sweden (2009). She is now a Senior Research Fellow in the Molecular and Cellular Biology laboratory based in the Postgraduate Medical Institute.
Chrissy’s Research has focused on identifying markers that may predict metastasis and response to neoadjuvant chemotherapy in breast cancer patients. She now concentrates on molecular diagnostics for cancer biomarkers. Chrissy also has an interest in holistic approach to cancer management for breast cancer patients with a specific focus on stress.
She maintains long running collaborations with senior researchers at Essex University (proteomics and breast cancer, Karolinska Institute (proteomics) and Imperial University, London (nanoparticles and targeted therapeutics for breast cancer). She has significant experience in translational clinical research and the use of human tissues in research working closely with clinicians in hospitals and pathology departments.
Chrissy is also involved in delivering training courses to PhD/Early career researchers (ECR) and has experience in lecturing at both undergraduate and postgraduate level. She currently supervises 5 MD/PhD students.
Bustin, S., Dhillon, H., Kirvell, S., Greenwood, C., Shipley, G.L. and Nolan, T. (2015). Variability of the reverse transcription step: practical implications. Clinical Chemistry, 16:1.
McVicar A, Ravalier JM & Greenwood C. (2013). Biology of Stress Revisited: Intracellular Mechanisms and the Conceptualization of Stress. Stress Health. e-publication
Metodieva G, Nogueira-de-Souza NC, Greenwood C, Al-janabi K, lengs L, Bucalas R, Metodiev M. (2013). CD74-dependent Deregulation of the Tumor Suppressor Scribble in Human Epithelial and Breast Cancer Cells. Neoplasia. 15 (6) pp660-668
Greenwood C, Gergana Metodieva, Khalid Al-Janabi, Berthold Lausen, Louise Alldridge, Lin Leng, Richard Bucala, Nelson Fernandez, and Metodi V. Metodiev. (2012). Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer J Proteomics. 75 (10) pp 3031-40.
Zakharchenko O, Greenwood C, Lewandowska A, Hellman U, Alldridge L, Souchelnytskyi S. (2011). Meta-data analysis as a strategy to evaluate individual and common features of proteomic changes in breast cancer. Cancer Genomics Proteomics. Jan-Feb;8(1):1-14.
Olena Zakharchenko,Christina Greenwood, Louise Alldridge and Serhiy Souchelnytskyi. (2011). Optimized Protocol for Protein Extraction from the Breast Tissue that is Compatible with Two-Dimensional Gel Electrophoresis. Breast Cancer: Basic and Clinical Research: March, 5 37-42
Greenwood C. (2014) Stress outcomes and cortisol responses in breast cancer patients receiving reflexology: A pilot randomised controlled trial. CAMSTRAND Conference. June .Christie NHS Foundation Trust, Manchester.
Greenwood C. (2013) Anxiety, cortisol and the effects of reflexology on breast cancer patients. CAMSTRAND Conference. July. University of Westminster
Greenwood, C. (2010). Identification of phosphoproteins involved in neoadjuvant chemotherapy responsiveness of breast tumours using proteomics. Essex Biomedical Sciences Institute (EBSI), First Annual Conference, Colchester Hospital, Essex, United Kingdom, 14th April.
Greenwood, C. (2009). Identification of phosphoproteins involved in primary chemotherapy responsiveness of breast tumours using proteomics. Cancer Center Karolinska workshop-retreat, Stockholm, Sweden, 27 August.
Greenwood, C. (2009). Evaluation of anxiety, salivary cortisol and melatonin secretion following reflexology treatment: A pilot study in healthy individuals. Focus on Methodology and Lessons Learned. CAMSTRAND Annual Conference, Middlesex University, Hendon Campus, London, United Kingdom, 30th April.